Crohn's disease is a non-specific inflammatory disease that usually affect the terminal ileum of the small intestine. It is characterized by inflammatory lesions called granulomas, though about 40% of sufferers do not appear to have well developed lesions. The lesions may not be localized to just the small intestine. Lesions have been known to appear in the mouth, esophagus, stomach, jejunum, and colon.
Crohn's disease presents with chronic diarrhea and abdominal pain. The lesion itself is ulcerative in nature and causes chronic damage tot he lining of the intestines causing malabsorption, nutritional deficiencies and weight loss.
Reference: Weatherby, D. (2004). Signs and Symptoms Analysis from a Functional Perspective. Jacksonville, OR: Bear Mountain Publishing.
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