Being keyed up all the time, and having difficult calming down is a sign of increased adrenal output, or hyperadrenalism. Increased cortisol with a concomitant low DHEA can cause these symptoms. In the beginning stages of adrenal decompensation the body's response to stress is to increase the cortisol output from the adrenal glands.
Reference: Weatherby, D. (2004).
Signs and Symptoms Analysis from a Functional Perspective. Jacksonville, OR: Bear Mountain Publishing
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